Viagra Sildenafil a Comprehensive Overview
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There are medicines that help you recover from cold and there are medicines that help you get an erection when you feel horny. It is that simple, if you think, and modern medical sciences have indeed revolutionized impotence treatment. The introduction of Viagra is 1998 was a remarkable event in the known history of mankind. It marked the beginning of a new kind of treatment. Earlier, people used to talk about impotence in hushed voices and with furtive glances. The problem was there, but remedies were few and far between. Also, most of those remedies were not safe and they created more problems than they solved. But approval by the US Food and Drug Administration made Viagra a safe pill to treat erectile problems among men of all ages.
What is Viagra?
Viagra is a tablet that gives you an erect penis when you want to have sex. It is a prescription drug, so you cannot get it unless recommended by your doctor. It has sildenafil as its active ingredient. An active ingredient is the actual drug that works. Viagra is only the trade name under which sildenafil is sold commercially.
A brief history of Viagra
Some researchers, who were working with a NY-based pharmaceutical company named Pfizer at the company’s lab in Kent, UK, discovered the potential of sildenafil as an effective drug for treating impotence. The compound was initially tested for treating high blood pressure and a heart problem. But clinical trials showed that sildenafil can bring on erections. Following this phenomenal discovery, Pfizer patented the compound in 1996 and decided to sell it under the brand name ‘Viagra’. Two years later, the FDA officially declared Viagra to be the first-of-its-kind oral medication indicated for the treatment of erectile problems. It hit the US market in the same year, amidst hypes and expectations. The current sales record of Viagra has made Pfizer the leading pharmaceutical company in the world.
How does sildenafil work?
Sildenafil is a PDE-5 inhibitor that works on an enzyme called PDE-5. This enzyme breaks down cGMP, a compound that plays a crucial role in dilating the penile arteries to ensure greater blood flow into the penis. So, the breakdown of cGMP by PDE-5 works against arterial expansion. The task of sildenafil is to selectively eliminate PDE-5 and help build up cGMP.
What dose of Viagra should I take?
Viagra comes in strengths of 25mg, 50mg and 100mg. The 50mg dose is usually recommended by doctors as a starter. But if you don’t get the hardness you’re looking for, you may be prescribed the highest dose. It all depends on your doctor. And if you’re aged over 65 years and are undergoing treatment for kidney or lever conditions, you should try the minimum Viagra dose of 25mg.
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Does Viagra have any competitors?
Fascinating as it is, Viagra doesn’t enjoy a monopoly in the global market. They year 2003 saw two more anti-impotence drugs entering the market and catching it by storms. Cialis tadalafil and Levitra vardenafil are the two other prescription medicines that are currently available on the market, along with Viagra sildenafil. They also have their loyal band of followers when it come to treating impotence. They are also PDE-5 inhibitors and work more or less in the same manner as Viagra does.
28. October 2011 at 13:26 Comments (0)



